The ESStim™ System

Imagine a technology that has the potential to improve the quality of life for millions of people and is 100% noninvasive?

Meet ESStim

Results Matter

Highland has completed multiple randomized double-blind placebo controlled clinical trials of ESStim™ for chronic pain, neurodegenerative, and psychiatric diseases. ESStim™ has consistently demonstrated significant benefits to patients in these investigational trials.

How Does it Work?

ESStim™ couples Transcranial Ultrasound (TUS) with Transcranial Direct Current Stimulation (tDCS) to focus, amplify, and steer transcranial applied currents. The physics of ESStim™ provide a multitude of neurostimulation advantages. ESStim™ is completely noninvasive, and the ElectroSonic approach offers greater focality, penetration, duration of neurostimulation effect, magnitude of neurostimulation effect, and targeting control than other noninvasive options. This has translated to significant benefits compared to other noninvasive neuromodulation approaches in randomized double-blind placebo controlled clinical trials.